Methylprednisolone
FULL PRESCRIBING INFORMATION: CONTENTS*
- METHYLPREDNISOLONE DESCRIPTION
- ACTIONS
- INDICATIONS & USAGE
- METHYLPREDNISOLONE CONTRAINDICATIONS
- WARNINGS
- USAGE IN PREGNANCY
- PRECAUTIONS
- DRUG INTERACTIONS
- INFORMATION FOR PATIENTS
- METHYLPREDNISOLONE ADVERSE REACTIONS
- DOSAGE & ADMINISTRATION
- HOW SUPPLIED
- STORAGE AND HANDLING
- PACKAGE LABEL.PRINCIPAL DISPLAY PANEL SECTION
FULL PRESCRIBING INFORMATION
METHYLPREDNISOLONE DESCRIPTION
ACTIONS
INDICATIONS & USAGE
1. Endocrine Disorders
Primary or secondary adrenocortical insuffciency (hydrocortisone or cortisone is the the first choice; synthetic analogs may be used in conjunction with mineralocorticoids where applicable; in infancy, mineralocorticoids supplementation is of particular importance).
2. Rheumatic Disorders
3. Collagen Diseases
4. Dermatologic Diseases
5. Allergic States
6. Ophthalmic Diseases
7. Respiratory Diseases
8. Hematologic Disorders
9. Neoplastic Diseases
10. Edematous States
11. Gastrointestinal Diseases
12. Nervous System
13. Miscellaneous
METHYLPREDNISOLONE CONTRAINDICATIONS
WARNINGS
1
2There may be decreased resistance and inability to localize infection when corticosteroids are used.
1
2
USAGE IN PREGNANCY
PRECAUTIONS
General PrecautionsDrug-induced secondary adrenocortical insuffciency may be minimized by gradual reduction of dosage. This type of relative insuffciency may persist for months after discontinuation of therapy; therefore, in any situation of stress occurring during that period, hormone therapy should be reinstituted. Since mineralocorticoid secretion may be impaired, salt and/or a mineralocorticoid should be administered concurrently.
DOSAGE AND ADMINISTRATION).
DRUG INTERACTIONS
INFORMATION FOR PATIENTS
METHYLPREDNISOLONE ADVERSE REACTIONS
Fluid and Electrolyte DisturbancesMusculoskeletal
Gastrointestinal
Dermatologic
Neurological
Endocrine
Ophthalmic
Metabolic
DOSAGE & ADMINISTRATION
IT SHOULD BE EMPHASIZED THAT DOSAGE REQUIREMENTS ARE VARIABLE AND MUST BE INDIVIDUALIZED ON THE BASIS OF THE DISEASE UNDER TREATMENT AND THE RESPONSE OF THE PATIENT.After a favorable response is noted, the proper maintenance dosage should be determined by decreasing the initial drug dosage in small decrements at appropriate time intervals until the lowest dosage which will maintain an adequate clinical response is reached. It should be kept in mind that constant monitoring is needed in regard to drug dosage. Included in the situations which may make dosage adjustments necessary are changes in clinical status secondary to remissions or exacerbations in the disease process, the patientcondition. If after long-term therapy the drug is to be stopped, it is recommended that it be withdrawn gradually rather than abruptly.
Multiple Sclerosis
Alternate Day Therapy
HOW SUPPLIED
STORAGE AND HANDLING
PACKAGE LABEL.PRINCIPAL DISPLAY PANEL SECTION
MethylprednisoloneMETHYLPREDNISOLONE TABLET
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PLEASE, BE CAREFUL!
Be sure to consult your doctor before taking any medication!
