Propranolol Hydrochloride
FULL PRESCRIBING INFORMATION: CONTENTS*
- PROPRANOLOL HYDROCHLORIDE DESCRIPTION
- CLINICAL PHARMACOLOGY
- PHARMACOKINETICS
- PHARMACODYNAMICS
- INDICATIONS & USAGE
- PROPRANOLOL HYDROCHLORIDE CONTRAINDICATIONS
- WARNINGS
- PRECAUTIONS
- DRUG INTERACTIONS
- CARCINOGENESIS & MUTAGENESIS & IMPAIRMENT OF FERTILITY
- PREGNANCY
- NURSING MOTHERS
- PEDIATRIC USE
- GERIATRIC USE
- PROPRANOLOL HYDROCHLORIDE ADVERSE REACTIONS
- OVERDOSAGE
- DOSAGE & ADMINISTRATION
- HOW SUPPLIED
- PACKAGE LABEL.PRINCIPAL DISPLAY PANEL SECTION
FULL PRESCRIBING INFORMATION
PROPRANOLOL HYDROCHLORIDE DESCRIPTION
CLINICAL PHARMACOLOGY
DOSAGE AND ADMINISTRATION
Mechanism of Action
PHARMACOKINETICS
Absorption
Distribution
Metabolism and Elimination
Enantiomers
Special Population
Geriatric
Gender
Race
Renal Insufficiency
Hepatic Insufficiency
PRECAUTIONS
Interactions with Substrates, Inhibitors or Inducers of Cytochrome P-450 Enzymes
Drug InteractionsPRECAUTIONS
Substrates or Inhibitors of CYP2D6
Substrates or Inhibitors of CYP1A2
Substrates or Inhibitors of CYP2C19
Inducers of Hepatic Drug Metabolism
Cardiovascular Drugs
Antiarrhythmics
Calcium Channel Blockers
Non-Cardiovascular Drugs
Migraine Drugs
Theophylline
Benzodiazepines
Neuroleptic Drugs
Anti-Ulcer Drugs
Lipid Lowering Drugs
PHARMACODYNAMICS
Hypertension
Angina Pectoris
Migraine
Hypertrophic Subaortic Stenosis
INDICATIONS & USAGE
HypertensionAngina Pectoris Due to Coronary Atherosclerosis
Migraine
Hypertrophic Subaortic Stenosis
PROPRANOLOL HYDROCHLORIDE CONTRAINDICATIONS
WARNINGS
Angina PectorisHypersensitivity and Skin Reactions
ADVERSE REACTIONS
ADVERSE REACTIONS
Cardiac Failure
Nonallergic Bronchospasm (e.g., Chronic Bronchitis, Emphysema)
Major Surgery
Diabetes and Hypoglycemia
Thyrotoxicosis
Wolff-Parkinson-White Syndrome
PRECAUTIONS
PRECAUTIONSGeneral
Clinical Laboratory Tests
DRUG INTERACTIONS
Drug InteractionsPHARMACOKINETICS AND DRUG METABOLISMCardiovascular Drugs
Antiarrhythmics
Digitalis Glycosides
Calcium Channel Blockers
Alpha Blockers
Reserpine
Inotropic Agents
OVERDOSAGE
Isoproterenol and Dobutamine
Non-Cardiovascular Drugs
Nonsteroidal Anti-Inflammatory Drugs
Antidepressants
Anesthetic Agents
Warfarin
Neuroleptic Drugs
Thyroxine
CARCINOGENESIS & MUTAGENESIS & IMPAIRMENT OF FERTILITY
PREGNANCY
Pregnancy Category CNURSING MOTHERS
PEDIATRIC USE
GERIATRIC USE
PROPRANOLOL HYDROCHLORIDE ADVERSE REACTIONS
Cardiovascular:
Central Nervous System:
Light-headedness; mental depression manifested by insomnia, lassitude, weakness, fatigue; catatonia; visual disturbances; hallucinations; vivid dreams; an acute reversible syndrome characterized by disorientation for time and place, short-term memory loss, emotional lability, slightly clouded sensorium, and decreased performance on neuropsychometrics. For immediate release formulations, fatigue, lethargy, and vivid dreams appear dose related.
Gastrointestinal:
Allergic:
Respiratory:
Hematologic:
Autoimmune:
Skin and mucous membranes:
Genitourinary:
OVERDOSAGE
Supportive Therapy:
DOSAGE & ADMINISTRATION
Hypertension
Angina Pectoris
WARNINGS
Migraine
Hypertrophic Subaortic Stenosis
HOW SUPPLIED
PACKAGE LABEL.PRINCIPAL DISPLAY PANEL SECTION
Propranolol HydrochloridePropranolol Hydrochloride CAPSULE, EXTENDED RELEASE
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PLEASE, BE CAREFUL!
Be sure to consult your doctor before taking any medication!
