Propranolol Hydrochloride
FULL PRESCRIBING INFORMATION: CONTENTS*
- PROPRANOLOL HYDROCHLORIDE DESCRIPTION
- CLINICAL PHARMACOLOGY
- PHARMACOKINETICS AND DRUG METABOLISM
- PHARMACODYNAMICS AND CLINICAL EFFECTS
- INDICATIONS & USAGE
- PROPRANOLOL HYDROCHLORIDE CONTRAINDICATIONS
- WARNINGS
- PRECAUTIONS
- LABORATORY TESTS
- DRUG INTERACTIONS
- CARCINOGENESIS & MUTAGENESIS & IMPAIRMENT OF FERTILITY
- PREGNANCY
- NURSING MOTHERS
- PEDIATRIC USE
- GERIATRIC USE
- PROPRANOLOL HYDROCHLORIDE ADVERSE REACTIONS
- OVERDOSAGE
- DOSAGE & ADMINISTRATION
- HOW SUPPLIED
- STORAGE AND HANDLING
- PACKAGE LABEL.PRINCIPAL DISPLAY PANEL SECTION
FULL PRESCRIBING INFORMATION
PROPRANOLOL HYDROCHLORIDE DESCRIPTION
CLINICAL PHARMACOLOGY
GeneralMechanism of Action
PHARMACOKINETICS AND DRUG METABOLISM
Absorption
Distribution
Metabolism and Elimination
Enantiomers
Special Populations
PRECAUTIONS
Drug Interactions
Drug InteractionsPRECAUTIONS
PHARMACODYNAMICS AND CLINICAL EFFECTS
HypertensionAngina Pectoris
Atrial Fibrillation
Myocardial Infarction
Migraine
Essential Tremor
Hypertrophic Subaortic Stenosis
Pheochromocytoma
INDICATIONS & USAGE
HypertensionAngina Pectoris Due to Coronary Atherosclerosis
Atrial Fibrillation
Myocardial Infarction
Migraine
Essential Tremor
Hypertrophic Subaortic Stenosis
Pheochromocytoma
PROPRANOLOL HYDROCHLORIDE CONTRAINDICATIONS
WARNINGS
Angina PectorisThere have been reports of exacerbation of angina and, in some cases, myocardial infarction, following abrupt discontinuance of propranolol therapy. Therefore, when discontinuance of propranolol is planned, the dosage should be gradually reduced over at least a few weeks and the patient should be cautioned against interruption or cessation of therapy without the physician's advice. If propranolol therapy is interrupted and exacerbation of angina occurs, it usually is advisable to reinstitute propranolol therapy and take other measures appropriate for the management of angina pectoris. Since coronary artery disease may be unrecognized, it may be prudent to follow the above advice in patients considered at risk of having occult atherosclerotic heart disease who are given propranolol for other indications.
Hypersensitivity and Skin Reactions
ADVERSE REACTIONS
ADVERSE REACTIONS
Cardiac Failure
In Patients without a History of Heart Failure,
Nonallergic Bronchospasm (e.g., Chronic Bronchitis, Emphysema)
Major Surgery
Diabetes and Hypoglycemia
Thyrotoxicosis
Wolff-Parkinson-White Syndrome
Pheochromocytoma
PRECAUTIONS
GeneralLABORATORY TESTS
DRUG INTERACTIONS
Drug InteractionsPHARMACOKINETICS AND DRUG METABOLISMOVERDOSAGE
CARCINOGENESIS & MUTAGENESIS & IMPAIRMENT OF FERTILITY
PREGNANCY
NURSING MOTHERS
PEDIATRIC USE
GERIATRIC USE
PROPRANOLOL HYDROCHLORIDE ADVERSE REACTIONS
Cardiovascular:
Central Nervous System:
Gastrointestinal:
Allergic:
Respiratory
Hematologic
Autoimmune:
Skin and mucous membranes:
Genitourinary
OVERDOSAGE
DOSAGE & ADMINISTRATION
GeneralHypertension
Angina Pectoris
WARNINGS
Atrial Fibrillation
Myocardial Infarction
PHARMACOKINETICS AND DRUG METABOLISM
Migraine
Essential Tremor
Hypertrophic Subaortic Stenosis
Pheochromocytoma
HOW SUPPLIED
STORAGE AND HANDLING
PACKAGE LABEL.PRINCIPAL DISPLAY PANEL SECTION
Propranolol HydrochloridePropranolol Hydrochloride TABLET
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PLEASE, BE CAREFUL!
Be sure to consult your doctor before taking any medication!
